According to data from the Global Burden of Disease Study, in 2015, HIV/AIDS was the leading cause of death among women of reproductive age around the world. While estimates differ depending on the particular global context, a 2013 review concluded that approximately 5% of pregnancy-related deaths worldwide and 25% of pregnancy-related deaths in sub-Saharan Africa are attributable to HIV. Women living with HIV in sub-Saharan Africa are at 6-8 times greater risk of dying during pregnancy or postpartum than their HIV-negative peers.
To mark World AIDS Day on December 1st, we compiled a list of 10 key papers related to HIV/AIDS and maternal health.
Prevalence and epidemiology
The contribution of HIV to pregnancy-related mortality: A systematic review and meta-analysis
AIDS | June 2013
Estimates of global, regional, and national incidence, prevalence, and mortality of HIV, 1980–2015: The Global Burden of Disease Study 2015
The Lancet | August 2016
HIV and the risk of direct obstetric complications: A systematic review and meta-analysis
PLOS One | October 2013
Systematic review of the proportion of pregnancy-related deaths attributed to HIV in population-based studies in sub-Saharan Africa
Tropical Medicine & International Health | January 2014
Barriers to prevention and treatment
A systematic review of individual and contextual factors affecting ART initiation, adherence, and retention for HIV-infected pregnant and postpartum women
PLOS One | November 2014
HIV-related stigma as a barrier to achievement of global PMTCT and maternal health goals: A review of the evidence
AIDS and Behavior | September 2013
Barriers and facilitating factors to the uptake of antiretroviral drugs for prevention of mother-to-child transmission of HIV in sub-Saharan Africa: A systematic review
Journal of the International AIDS Society | July 2013
Programs and interventions
Community innovation: Achieving sexual and reproductive health and rights for women and girls through the HIV response
UNAIDS | 2011
Interventions to prevent sexually-transmitted infections, including HIV, among young people in low- and middle-income countries: A systematic review of the published and gray literature
Journal of Adolescent Health | September 2016
Health systems integration of sexual and reproductive health and HIV services in sub-Saharan Africa: A scoping study
Journal of Acquired Immune Deficiency Syndromes | December 2014
Learn more about HIV/AIDS and maternal health.
Check out the MHTF blog series Maternal Health, HIV & AIDS.