According to data from the Global Burden of Disease Study, in 2015, HIV/AIDS was the leading cause of death among women of reproductive age around the world. While estimates differ depending on the particular global context, a 2013 review concluded that approximately 5% of pregnancy-related deaths worldwide and 25% of pregnancy-related deaths in sub-Saharan Africa are attributable to HIV. Women living with HIV in sub-Saharan Africa are at 6-8 times greater risk of dying during pregnancy or postpartum than their HIV-negative peers.
Prevalence and epidemiology
HIV and the risk of direct obstetric complications: A systematic review and meta-analysis
PLOS One | October 2013
Systematic review of the proportion of pregnancy-related deaths attributed to HIV in population-based studies in sub-Saharan Africa
Tropical Medicine & International Health | January 2014
Barriers to prevention and treatment
HIV-related stigma as a barrier to achievement of global PMTCT and maternal health goals: A review of the evidence
AIDS and Behavior | September 2013
Barriers and facilitating factors to the uptake of antiretroviral drugs for prevention of mother-to-child transmission of HIV in sub-Saharan Africa: A systematic review
Journal of the International AIDS Society | July 2013
Programs and interventions
Interventions to prevent sexually-transmitted infections, including HIV, among young people in low- and middle-income countries: A systematic review of the published and gray literature
Journal of Adolescent Health | September 2016
Health systems integration of sexual and reproductive health and HIV services in sub-Saharan Africa: A scoping study
Journal of Acquired Immune Deficiency Syndromes | December 2014
Learn more about HIV/AIDS and maternal health.
Check out the MHTF blog series Maternal Health, HIV & AIDS.